{"id":7858,"date":"2026-10-05T09:33:09","date_gmt":"2026-10-05T06:33:09","guid":{"rendered":"https:\/\/www.nlc.cy\/?p=7858"},"modified":"2026-10-05T11:14:49","modified_gmt":"2026-10-05T08:14:49","slug":"tozorakimab-xap-oberon-titania","status":"publish","type":"post","link":"https:\/\/www.nlc.cy\/el\/2026\/10\/05\/tozorakimab-xap-oberon-titania\/","title":{"rendered":"Tozorakimab \u03c3\u03c4\u03b7 \u03a7\u0391\u03a0: \u03bd\u03ad\u03bf \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2"},"content":{"rendered":"<p><\/p>\n<p>\u0397 <strong>\u03a7\u03c1\u03cc\u03bd\u03b9\u03b1 \u0391\u03c0\u03bf\u03c6\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03a0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 (\u03a7\u0391\u03a0)<\/strong> \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03bc\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b1\u03b9\u03c4\u03af\u03b5\u03c2 \u03bd\u03bf\u03c3\u03b7\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2. \u03a0\u03b1\u03c1\u03ac \u03c4\u03b7 \u03c3\u03cd\u03b3\u03c7\u03c1\u03bf\u03bd\u03b7 \u03b5\u03b9\u03c3\u03c0\u03bd\u03b5\u03cc\u03bc\u03b5\u03bd\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03b1\u03c1\u03ba\u03b5\u03c4\u03bf\u03af \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b5\u03be\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03c3\u03b5 \u03b5\u03c0\u03b9\u03b4\u03b5\u03af\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2, \u03b5\u03c0\u03b9\u03c3\u03ba\u03ad\u03c8\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b1 \u03b5\u03c0\u03b5\u03af\u03b3\u03bf\u03bd\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03bf\u03c3\u03b7\u03bb\u03b5\u03af\u03b5\u03c2.<\/p>\n<p>\u039d\u03ad\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03b4\u03cd\u03bf \u03bc\u03b5\u03b3\u03ac\u03bb\u03b5\u03c2 \u03c4\u03c5\u03c7\u03b1\u03b9\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 3 <strong>OBERON<\/strong> \u03ba\u03b1\u03b9 <strong>TITANIA<\/strong> \u03b4\u03b5\u03af\u03c7\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03c4\u03bf <strong>tozorakimab<\/strong>, \u03ad\u03bd\u03b1 \u03c5\u03c0\u03cc \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03bc\u03bf\u03bd\u03bf\u03ba\u03bb\u03c9\u03bd\u03b9\u03ba\u03cc \u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c4\u03bf\u03c7\u03b5\u03cd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b9\u03bd\u03c4\u03b5\u03c1\u03bb\u03b5\u03c5\u03ba\u03af\u03bd\u03b7-33 (IL-33), \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b9\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 \u03a7\u0391\u03a0 \u03cc\u03c4\u03b1\u03bd \u03c0\u03c1\u03bf\u03c3\u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c3\u03c5\u03bd\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2.<\/p>\n<h2>\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf tozorakimab;<\/h2>\n<p>\u03a4\u03bf tozorakimab \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 <strong>IL-33<\/strong>, \u03bc\u03b9\u03b1\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03bf\u03ba\u03af\u03bd\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03c4\u03c9\u03bd \u03b1\u03b5\u03c1\u03b1\u03b3\u03c9\u03b3\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03b8\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03a7\u0391\u03a0. \u0397 \u03c0\u03c1\u03bf\u03c3\u03ad\u03b3\u03b3\u03b9\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03ba\u03b1\u03b8\u03b9\u03b5\u03c1\u03c9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b5\u03b9\u03c3\u03c0\u03bd\u03b5\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03b2\u03b1\u03c3\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03b4\u03b9\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9, \u03c3\u03b5 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2, \u03b5\u03b9\u03c3\u03c0\u03bd\u03b5\u03cc\u03bc\u03b5\u03bd\u03b1 \u03ba\u03bf\u03c1\u03c4\u03b9\u03ba\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ae.<\/p>\n<h2>\u03a4\u03b9 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c3\u03b1\u03bd \u03bf\u03b9 OBERON \u03ba\u03b1\u03b9 TITANIA;<\/h2>\n<p>\u039f\u03b9 OBERON \u03ba\u03b1\u03b9 TITANIA \u03ae\u03c4\u03b1\u03bd \u03b4\u03cd\u03bf \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03b5\u03c2, \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf\u03c5 \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 3. \u03a3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03af\u03c7\u03b1\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03a7\u0391\u03a0 \u03c0\u03bf\u03c5 \u03ae\u03c4\u03b1\u03bd \u03bd\u03c5\u03bd \u03ae \u03c0\u03c1\u03ce\u03b7\u03bd \u03ba\u03b1\u03c0\u03bd\u03b9\u03c3\u03c4\u03ad\u03c2, \u03b5\u03af\u03c7\u03b1\u03bd \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b9\u03b6\u03b1\u03bd \u03bd\u03b1 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c0\u03b1\u03c1\u03ac \u03c4\u03b7 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c3\u03c5\u03bd\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2.<\/p>\n<p>\u039f\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03b5\u03af\u03c4\u03b5 <strong>tozorakimab 300 mg \u03c5\u03c0\u03bf\u03b4\u03bf\u03c1\u03af\u03c9\u03c2 \u03ba\u03ac\u03b8\u03b5 4 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong> \u03b5\u03af\u03c4\u03b5 placebo, \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03c4\u03b7\u03c2 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03c3\u03b1\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5\u03c2, \u03b3\u03b9\u03b1 52 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2. \u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03bf \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03ad\u03c7\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03ad\u03bd\u03c4\u03b1\u03be\u03b7 \u03c3\u03c4\u03b9\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 <strong>\u03b4\u03b5\u03bd \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03c3\u03b5 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03b7\u03c9\u03c3\u03b9\u03bd\u03bf\u03c6\u03af\u03bb\u03c9\u03bd \u03c3\u03c4\u03bf \u03b1\u03af\u03bc\u03b1<\/strong>.<\/p>\n<h2>\u03a0\u03cc\u03c3\u03bf \u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b1\u03bd \u03bf\u03b9 \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2;<\/h2>\n<p>\u03a3\u03c4\u03bf\u03c5\u03c2 \u03c0\u03c1\u03ce\u03b7\u03bd \u03ba\u03b1\u03c0\u03bd\u03b9\u03c3\u03c4\u03ad\u03c2, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03bf\u03b9 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03b1\u03bd \u03c4\u03bf\u03bd \u03ba\u03cd\u03c1\u03b9\u03bf \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7\u03c2, \u03c4\u03bf tozorakimab \u03bc\u03b5\u03af\u03c9\u03c3\u03b5 \u03c4\u03bf\u03bd \u03b5\u03c4\u03ae\u03c3\u03b9\u03bf \u03c1\u03c5\u03b8\u03bc\u03cc \u03bc\u03ad\u03c4\u03c1\u03b9\u03c9\u03bd \u03ae \u03c3\u03bf\u03b2\u03b1\u03c1\u03ce\u03bd \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03c9\u03bd:<\/p>\n<ul>\n<li><strong>OBERON:<\/strong> \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 29% \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7.<\/li>\n<li><strong>TITANIA:<\/strong> \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 34% \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7.<\/li>\n<\/ul>\n<p>\u038c\u03c4\u03b1\u03bd \u03b1\u03bd\u03b1\u03bb\u03cd\u03b8\u03b7\u03ba\u03b5 \u03bf \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03cc\u03c2 \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc\u03c2, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c0\u03c1\u03ce\u03b7\u03bd \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b5\u03c1\u03b3\u03ce\u03bd \u03ba\u03b1\u03c0\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd, \u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b5\u03b9\u03bd\u03b5 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03c3\u03c4\u03bf <strong>29\u201330%<\/strong>.<\/p>\n<h2>\u0393\u03b9\u03b1\u03c4\u03af \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03bf \u03b5\u03cd\u03c1\u03b7\u03bc\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03b7\u03c9\u03c3\u03b9\u03bd\u03cc\u03c6\u03b9\u03bb\u03b1;<\/h2>\n<p>\u039f\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bd\u03b5\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03c3\u03c4\u03b7 \u03a7\u0391\u03a0 \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03c4\u03cd\u03c0\u03bf\u03c5 2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 \u03b7\u03c9\u03c3\u03b9\u03bd\u03cc\u03c6\u03b9\u03bb\u03b1. \u03a3\u03c4\u03b9\u03c2 OBERON \u03ba\u03b1\u03b9 TITANIA, \u03b7 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03b4\u03b5\u03bd \u03b5\u03be\u03b1\u03c1\u03c4\u03b9\u03cc\u03c4\u03b1\u03bd \u03b1\u03c0\u03cc \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b7\u03c9\u03c3\u03b9\u03bd\u03bf\u03c6\u03af\u03bb\u03c9\u03bd. \u0391\u03c5\u03c4\u03cc \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03b3\u03b9\u03b1 \u03c4\u03bf \u03b5\u03bd\u03b4\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03bf \u03c4\u03bf tozorakimab \u03bd\u03b1 \u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03bf \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd \u03ad\u03bd\u03b1 \u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03bf \u03c6\u03ac\u03c3\u03bc\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03a7\u0391\u03a0 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b5\u03c2 \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2.<\/p>\n<h2>\u03a4\u03b9 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03c5\u03bc\u03b5 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1;<\/h2>\n<p>\u0397 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ae \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b1\u03bd\u03b5\u03c0\u03b9\u03b8\u03cd\u03bc\u03b7\u03c4\u03c9\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03b5\u03b9\u03ce\u03bd \u03ae\u03c4\u03b1\u03bd \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03bf\u03bc\u03ac\u03b4\u03c9\u03bd tozorakimab \u03ba\u03b1\u03b9 placebo \u03c3\u03c4\u03b9\u03c2 \u03b4\u03cd\u03bf \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2. \u03a4\u03b1 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b4\u03b5\u03bd \u03b1\u03bd\u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03ad\u03c2 \u03bd\u03ad\u03bf \u03c3\u03ae\u03bc\u03b1 \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1\u03c2, \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b7 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03b5\u03c4\u03b1\u03b9.<\/p>\n<h2>\u0391\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03a7\u0391\u03a0;<\/h2>\n<p><strong>\u038c\u03c7\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7.<\/strong> \u03a4\u03bf tozorakimab \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf \u03c0\u03b1\u03c1\u03cc\u03bd \u03ba\u03b1\u03b8\u03b9\u03b5\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03a7\u0391\u03a0. \u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd OBERON \u03ba\u03b1\u03b9 TITANIA \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b5\u03bd\u03b8\u03b1\u03c1\u03c1\u03c5\u03bd\u03c4\u03b9\u03ba\u03ac, \u03b1\u03bb\u03bb\u03ac \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c5\u03c0\u03cc \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7.<\/p>\n<p>\u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03a7\u0391\u03a0 \u03b4\u03b5\u03bd \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd \u03c4\u03b7\u03bd \u03b5\u03b9\u03c3\u03c0\u03bd\u03b5\u03cc\u03bc\u03b5\u03bd\u03b7 \u03ae \u03ac\u03bb\u03bb\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03c3\u03c5\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03cc\u03b3\u03bf \u03c4\u03bf\u03c5\u03c2.<\/p>\n<h2>\u03a4\u03bf \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1<\/h2>\n<p>\u039f\u03b9 \u03b4\u03cd\u03bf \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 3 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03bc\u03b5 \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1 \u03cc\u03c4\u03b9 \u03b7 \u03c0\u03c1\u03bf\u03c3\u03b8\u03ae\u03ba\u03b7 \u03c4\u03bf\u03c5 tozorakimab \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c3\u03c5\u03bd\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2 \u03bc\u03b5\u03af\u03c9\u03c3\u03b5 \u03ba\u03b1\u03c4\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 <strong>30% \u03c4\u03b9\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 \u03a7\u0391\u03a0<\/strong>. \u0395\u03ac\u03bd \u03c4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03c9\u03b8\u03bf\u03cd\u03bd \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03ac\u03be\u03b7 \u03ba\u03b1\u03b9 \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03b8\u03b5\u03af \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03ce\u03c2 \u03b7 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1, \u03b7 \u03c3\u03c4\u03cc\u03c7\u03b5\u03c5\u03c3\u03b7 \u03c4\u03b7\u03c2 IL-33 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03b5\u03b9 \u03bc\u03af\u03b1 \u03bd\u03ad\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ae \u03b3\u03b9\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03a7\u0391\u03a0 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03b5\u03c2 \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2.<\/p>\n<h2>\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/h2>\n<ol>\n<li>Sciurba FC, Watz H, Bourdin A, et al. <em>Tozorakimab to Prevent COPD Exacerbations.<\/em> New England Journal of Medicine. Published online September 8, 2026. doi:10.1056\/NEJMoa2606998.<\/li>\n<li>OBERON and TITANIA Phase III trials, presented at the European Respiratory Society Congress 2026.<\/li>\n<\/ol>\n<p><em>\u03a4\u03bf \u03c0\u03b5\u03c1\u03b9\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03bf \u03ad\u03c7\u03b5\u03b9 \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03c9\u03c4\u03b9\u03ba\u03cc \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03ae\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03c5\u03c0\u03bf\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7.<\/em><\/p>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>\u039d\u03ad\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 OBERON \u03ba\u03b1\u03b9 TITANIA \u03b4\u03b5\u03af\u03c7\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03c4\u03bf tozorakimab \u03bc\u03b5\u03af\u03c9\u03c3\u03b5 \u03ba\u03b1\u03c4\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 30% \u03c4\u03b9\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 \u03a7\u0391\u03a0.<\/p>\n","protected":false},"author":1,"featured_media":7865,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"\u039d\u03ad\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 OBERON \u03ba\u03b1\u03b9 TITANIA: \u03c4\u03bf tozorakimab \u03bc\u03b5\u03af\u03c9\u03c3\u03b5 \u03ba\u03b1\u03c4\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 30% \u03c4\u03b9\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c0\u03b1\u03c1\u03bf\u03be\u03cd\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 \u03a7\u0391\u03a0.","jetpack_seo_html_title":"Tozorakimab \u03c3\u03c4\u03b7 \u03a7\u0391\u03a0: \u03bd\u03ad\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 OBERON & TITANIA","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[22],"tags":[],"class_list":["post-7858","post","type-post","status-publish","format-standard","has-post-thumbnail","category-22","czr-hentry"],"jetpack_publicize_connections":[],"jetpack_shortlink":"https:\/\/wp.me\/pbNX90-22K","jetpack-related-posts":[],"jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.nlc.cy\/wp-content\/uploads\/2026\/10\/IMG_9707.png?fit=1170%2C350&ssl=1","_links":{"self":[{"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/posts\/7858","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/comments?post=7858"}],"version-history":[{"count":4,"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/posts\/7858\/revisions"}],"predecessor-version":[{"id":7866,"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/posts\/7858\/revisions\/7866"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/media\/7865"}],"wp:attachment":[{"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/media?parent=7858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/categories?post=7858"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nlc.cy\/el\/wp-json\/wp\/v2\/tags?post=7858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}